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Flumil, the most common antimucolytic

Flumil is a mucolytic medication , that is, it decreases nasal mucus. The active principle it contains is acetylcysteine , which can also be used as an antidote in an overdose of paracetamol . It is used orally as a symptomatic treatment of bronchitis, cystic fibrosis and other pulmonary pathologies that occur with an excess of mucus. Mechanism of action of acetylcysteine ​​(Flumil) As we have said, flumil is a mucolytic drug. The abundant mucus that we have when we have a cold is a set of secretions from the mucosa

Methotrexate: what it is and how it acts

Methotrexate is a medicine that belongs to a group of drugs called antimetabolites. This means that its structure is similar to that of molecules of our organism (metabolites), which is why they bind to the same receptors. If the drug is bound to the receptor, the original metabolite can not do so, thus decreasing its effect. Methotrexate is analogous to folic acid, also known as vitamin B9. It is used in the treatment of autoimmune diseases and as part of antineoplastic therapy. What is folic acid? Folic acid is

Barbiturates: mechanism of action

Barbiturates are a wide variety of drugs derived from barbituric acid , an organic compound based on the structure of pyrimidine. These drugs have the ability to sedate the central nervous system producing an extensive scheme of effects, from mild sedation to the total anesthesia of the individual. Barbiturates also have analgesic effects, however, their effects are mild so they must be accompanied by other analgesics in case of surgery. Other uses that have been given to barbiturates are: Characteristics of barbiturates The barbiturates were synthesized for the first time in

Promethazine: what it is and how it acts

Promethazine is a drug in the phenothiazine family, used in the treatment of mental and emotional disorders and to reduce nausea. Its activity is based on reducing the levels of histamine in the body. Promethazine has no neuroleptic effects, although it is very useful in the symptomatic treatment of allergies, reducing the discomfort of rhinitis and allergic conjunctivitis.    Histamine and allergy Histamine is a brain neurotransmitter (chemicals released during neuronal communication) and an endogenous amine. It is stored in granules that can be found inside some cells, such as mast cells

Chloramphenicol: what it is and how it acts

Chloramphenicol is a drug belonging to the group of antibiotics or antimicrobials. Its mechanism of action consists of inhibiting or deactivating certain functions performed by some bacteria (fundamentally participating in the mechanisms involved in protein synthesis). In this way, the bacteria fail to produce the proteins necessary to maintain their biological cycle and die as a result of abnormal development. Applications of chloramphenicol Among the bacteria affected by chloramphenicol, we can include those belonging to the genus Salmonella (causing salmonellosis and typhoid fever). Likewise, it affects bacteria of the Rickettsia genus

Domperidone: what it is and how it acts

Domperidone is a drug with antiemetic and prokinetic properties, that is, it prevents vomiting and improves intestinal transit. Here we will explain in more detail different aspects about this drug: Mechanism of action Pharmacokinetics Pharmacological actions Adverse reactions Interactions Mechanism of action Domperidone is a drug with a structure similar to that of butyrophenones (known antipsychotics) that acts peripherally. By not crossing the , it binds to its receptors in the postrema area. The postrema area is a medullar

Treatment of renal lithiasis

Renal lithiasis, or kidney stones, are solid masses that are formed by aggregation of small mineral particles. They usually originate in the kidneys, but can develop anywhere along the urinary tract, including the kidneys, ureters, bladder and urethra. It is known that kidney stones are one of the most painful medical conditions. Recognizing the symptoms and signs of a kidney stone Kidney stones cause severe pain. The symptoms may not appear until the stone is inserted into the ureters, a condition known as renal colic. The pain spreads to the

Amoxicillin

Amoxicillin is a penicillin antibiotic, belonging to the β-lactams, with the ability to interfere in the synthesis of the bacterial wall . The ß-lactam antibiotics, such as amoxicillin, are widely used antibacterials since they have good pharmacokinetic characteristics in general, since some must be administered parenterally and have a relatively wide margin of safety. How does this medicine work in the body? Amoxicillin is an antibiotic capable of inhibiting the synthesis of the wall of bacteria. Due to this characteristic, microorganisms that lack a cell wall will be resistant to this

Diazepam: what it is and what it is used for

Diazepam is a medication of the benzodiazepine group. It acts on the central nervous system with anxiolytic, sedative and anticonvulsant effects. It is long-acting and its use is widespread in anxiety disorders, epileptic seizures and febrile disorders or as a muscle relaxant. How does diazepam work? Diazepam is a central nervous system depressant, that is, it decreases the activity of neuronal circuits. It acts mainly in the limbic system, thalamus and hypothalamus. This depressing action is due to   Diazepam potentiates the action of an inhibitory neurotransmitter called gamma-aminobutyric

Gabapentina: what it is and what it is used for

Gabapentin is a medicine used in the treatment of certain types of epilepsy . It successfully avoids the crises and convulsions characteristic of the disease. Our body is not able to metabolize it, so it is eliminated mainly by urine. Currently, we also find it to relieve pain (analgesic) associated with certain neurological diseases. In this category we include the illness caused by the herpes virus in adults (herpes zoster) and for the restless legs syndrome ( Willis-Ekbom disease ). These disorders are usually associated with nerve damage. Pharmacology of

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